Status:
COMPLETED
Use of Injectable Platelet Rich Fibrin in Lichen Planus
Lead Sponsor:
Bezmialem Vakif University
Conditions:
Lichen Planus
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Platelet Rich Fibrine (PRF), which promotes wound healing by supporting angiogenesis, immunity and epithelial proliferation phases. over a decade has since past since PRF was developed and many clinic...
Detailed Description
Lichen planus diagnosis will be made histopathologically. Intraoral photographs and measurements will be taken at the beginning of the treatment and 2 months after the treatment is finished.
Eligibility Criteria
Inclusion
- Oral erosive lesions were diagnosed according to Andreasen classification.
- Histological confirmation of erosive OLP according to the World Health Organization's clinicopathological diagnostic criteria for OLP.
- No previous treatment of oral lichen planus at least 3 months.
- Willingness and ability to complete the present clinical trial.
- Patients of ages above 18 years old without skin involvement.
Exclusion
- Histological signs of dysplasia.
- Using drugs associated with lichenoid reaction.
- Pregnant, lactating and smoker patients.
- Patient with systemic diseases such as diabetes mellitus, immunodysfunction, hematological and hepatological patients or had photosensitivity history.
Key Trial Info
Start Date :
May 3 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 2 2019
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT03265093
Start Date
May 3 2017
End Date
September 2 2019
Last Update
May 28 2020
Active Locations (1)
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1
Ebru SAĞLAM
Istanbul, Fatih, Turkey (Türkiye), 34093