Status:
COMPLETED
Renal Protection of Intravenous Dexmedetomidine During Radical Cystectomy
Lead Sponsor:
Mansoura University
Conditions:
Radical Cystectomy
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
Acute kidney injury and chronic kidney disease usually associated with radical cystectomy operation which is the treatment of choice for invasive urinary bladders tumor. Peri-operative acute kidney in...
Detailed Description
The aim of this study is to test the hypothesis that intra-operative intravenous dexmedetomidine infusion could improve early renal function after open radical cystectomy. This randomized comparative...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists physical status I or II.
- Patients scheduled for elective radical cystectomy.
Exclusion
- Serum creatinine level equal or greater than 1.4 mg/dl.
- Allergy to alpha-2 adrenergic agonist
- Allergy to any anesthetic drugs
- Uncontrolled hypertension.
- Uncontrolled diabetes.
- Heart block greater than first degree.
- History of alcohol abuse.
- History of drug abuse.
- Clinically significant neurologic disease.
- Clinically significant cardiovascular disease.
- Clinically significant respiratory disease.
- Clinically significant hepatic disease.
Key Trial Info
Start Date :
December 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 30 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03265470
Start Date
December 1 2015
End Date
August 30 2020
Last Update
September 9 2020
Active Locations (1)
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1
Mansoura university
Al Mansurah, Dakahlia Governorate, Egypt, 050