Status:

TERMINATED

Investigation of Oscillations Underlying Human Cognitive and Affective Processing Using Intracranial EEG

Lead Sponsor:

University of North Carolina, Chapel Hill

Collaborating Sponsors:

National Institute of Neurological Disorders and Stroke (NINDS)

Conditions:

Working Memory

Emotions

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Purpose: To investigate the electrophysiological correlates of human cognition and affective processing. Participants: Drug-resistant epilepsy patients undergoing epilepsy surgery cortical mapping wit...

Detailed Description

Oscillations in different frequency bands like theta, alpha, beta, gamma and high gamma are thought to underlie processing of cognitive and emotional information. For example, theta (3 - 7 Hz) and alp...

Eligibility Criteria

Inclusion

  • History of medically intractable epilepsy
  • Capable of giving informed consent
  • Aged 18 - 80 years, either sex

Exclusion

  • Major systemic illness
  • Severe cognitive impairment defined as mini-mental state examination of less than 20
  • Severe psychiatric illness
  • Excessive use of alcohol or other substances

Key Trial Info

Start Date :

August 7 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 29 2018

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT03268694

Start Date

August 7 2017

End Date

July 29 2018

Last Update

January 13 2020

Active Locations (1)

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University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, United States, 27599

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