Status:

COMPLETED

Safety and Efficacy of FURESTEM-AD Inj. in Patients With Moderate to Severe Chronic Atopic Dermatitis(AD)

Lead Sponsor:

Kang Stem Biotech Co., Ltd.

Conditions:

Atopic Dermatitis

Eligibility:

All Genders

19+ years

Phase:

PHASE3

Brief Summary

This is multi-center, randomized, double-blind, parallel, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of FURESTEM-AD Inj. for moderate to severe chronic atopic derm...

Eligibility Criteria

Inclusion

  • Of either gender, aged \>=19
  • Atopic Dermatitis subjects who are coincident with Hanifin and Rajka diagnosis criteria
  • Chronic Atopic Dermatitis that has been present for at least 3 years
  • EASI\>=12 at screening and baseline visit
  • IGA\>=3, SCORAD index\>=25, BSA \>=10% of AD involvement at screegning and baseline visit
  • Subjects with documented record of inadequate response to the stable use of topical atopic dermatitis treatment within 24 weeks before participating in the study, or whom are inadvisable due to safety risks
  • Subjects who understand and voluntarily sign an informed consent form

Exclusion

  • Subjects with medical history or surgery/procedure history
  • Subjects with diseases at the time of participation in this study (systemic infection, other serious skin disorders, pigmentation or extensive scarring in atopic dermatitis symptom region)
  • Subjects who need prohibited medication during clinical period
  • Pregnant, breast-feeding women or women who plan to become pregnant during this study
  • Subjects who currently participate in other clinical trial or participated in other clinical trial within 4 weeks
  • Any other condition which the investigator judges would make patient unsuitable for study participation

Key Trial Info

Start Date :

April 25 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 20 2019

Estimated Enrollment :

197 Patients enrolled

Trial Details

Trial ID

NCT03269773

Start Date

April 25 2018

End Date

June 20 2019

Last Update

September 12 2019

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Pusan National University Hospital

Busan, South Korea

2

Chonnam National University Hospital

Gwangju, South Korea

3

Dongguk University Medical Center

Ilsan, South Korea

4

Gachon University Gil Medical Center

Incheon, South Korea