Status:
COMPLETED
The Effect of Remote Ischemic Preconditioning on Kidney Function in Patients Undergoing Partial Nephrectomy
Lead Sponsor:
Seoul National University Hospital
Conditions:
Renal Neoplasm
Renal Injury
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
This study is intended to evaluate the renal protective effect of Remote Ischemic Preconditioning (RIPC) in patients undergoing partial nephrectomy. Half of the enrolled subjects will receive 4 cycles...
Detailed Description
Remote Ischemic Preconditioning (RIPC) is the concept of mitigating ischemia-reperfusion injury to target organs by a brief episode of ischemia-reperfusion of the limb. The protective effect of RIPC o...
Eligibility Criteria
Inclusion
- Adult patients scheduled to undergo open, laparoscopic, or robot-assisted laparoscopic partial nephrectomy
- Normal contralateral renal function was defined as split renal function of \>40% as determined by preoperative Tc-99m DiethyleneTriamine Pentaacetic Acid (DTPA) kidney scan
- Written informed consent
Exclusion
- Peripheral vascular disease involving upper extremities or lower extremities
- Severe cardiopulmonary diseases (valvular or ischemic heart disease, heart failure, chronic obstructive pulmonary disease)
- Hepatic failure, renal failure
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 28 2018
Estimated Enrollment :
86 Patients enrolled
Trial Details
Trial ID
NCT03273751
Start Date
September 1 2017
End Date
August 28 2018
Last Update
October 21 2021
Active Locations (1)
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1
Seoul National University Hospital
Seoul, South Korea, 03080