Status:
WITHDRAWN
Trabeculectomy Versus 2-iStent and Prostaglandin Study
Lead Sponsor:
Johns Hopkins University
Conditions:
Glaucoma, Open-Angle
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
Investigators hypothesize that the synergistic action of iStent in increasing aqueous outflow through the trabecular meshwork and use of prostaglandin analog such as travoprost or latanoprost to incre...
Detailed Description
This will be a prospective randomized controlled study. 20 phakic or pseudophakic open angle glaucoma patients with an IOP in the range of 18-30 mmHg on 2 or more topical glaucoma medications will be...
Eligibility Criteria
Inclusion
- Patients who have mental capacity to give consent
- Age \>= 21 years
- Pseudophakic or phakic without visually significant cataract
- Open angle glaucoma
- IOP in the range of 18-30 mmHg with 2 or more topical medications
- Cup-disc ratio =\< 0.9
- Best corrected visual acuity of 20/100 or better
Exclusion
- Inability to give consent
- Inability to tolerate or presence of allergy to prostaglandin analogs
- Patient preference for non-surgical treatment or preference for either of the recommended surgical modalities in the study
- Age \< 21 years
- Visually significant cataract that would benefit from cataract surgery, as determined by the treating surgeon in consultation with the patient
- Secondary glaucoma or angle closure glaucoma
- Aphakia
- Prior glaucoma incisional surgery (trabeculectomy, tube surgery, other Microinvasive Glaucoma Surgery (MIGS) surgeries, deep sclerectomy)
- Prior laser trabeculoplasty \< 90 days prior to screening or absolute failure of prior laser trabeculoplasty.
Key Trial Info
Start Date :
January 12 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 12 2018
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03274323
Start Date
January 12 2018
End Date
January 12 2018
Last Update
January 19 2018
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