Status:

COMPLETED

Theta Burst Stimulation to Promote Motor Re-education in Tetraplegia

Lead Sponsor:

Virginia Commonwealth University

Collaborating Sponsors:

Medical University of South Carolina

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Quadriplegia/Tetraplegia

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

A repetitive, non-invasive brain stimulation technique referred to as theta burst stimulation can modulate corticomotor excitability and therefore has great rehabilitative potential for individuals wi...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for all subjects with tetraplegia:
  • Injury to the lower cervical spinal cord at least one year prior to the date of participation
  • Motor function classified according to the American Spinal Injury Association International Standards for Neurological Classification of Spinal Cord Injury at levels ranging from C5-C8
  • Inclusion criteria for the subjects with tetraplegia and upper limb reconstruction:
  • • At least one year post-operative from tendon or nerve transfer surgery of the upper limb
  • Exclusion criteria for all subjects with tetraplegia:
  • Presence of concurrent severe medical illness, including unhealed decubiti, use of baclofen pumps, existing infection, cardiovascular disease, significant osteoporosis, or a history of pulmonary complications.
  • Metal implant near head or neck
  • Risk of seizure of history of seizures

Exclusion

    Key Trial Info

    Start Date :

    April 16 2018

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    February 28 2020

    Estimated Enrollment :

    19 Patients enrolled

    Trial Details

    Trial ID

    NCT03277521

    Start Date

    April 16 2018

    End Date

    February 28 2020

    Last Update

    November 17 2020

    Active Locations (1)

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    Virginia Commonwealth University

    Richmond, Virginia, United States, 23219