Status:
COMPLETED
Angiography for Evaluation of the Feeder Vessel in EUS-guided Coils and Cyanoacrylate Therapy for Gastric Varices
Lead Sponsor:
Instituto Ecuatoriano de Enfermedades Digestivas
Conditions:
Gastric Varices
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
INTRODUCTION: Bleeding from gastric varices (GV) is associated with a high mortality rate. Injection of cyanoacrylate (CYA) using standard gastroscope has demonstrated to achieve higher hemostasis and...
Detailed Description
On the other hand, despite the EUS-injection of coils and CYA have shown very promising results, it is extremely important to have experience performing this technique, as the injection in a wrong ves...
Eligibility Criteria
Inclusion
- Patients above 18 years old with gastric varices (GV) on the initial standard diagnostic upper endoscopy will be enrolled. GV will be classified
- Only gastro-esophageal varices type II (GOV II) (fundal varices communicating with esophageal varices) and isolated gastric varices type I (IGV I) (fundal varices within a few centimeters of the gastric cardia) will be included (according to Sarin and Kumar classification).
- Patients with active bleeding and history of previous bleeding due to GV (secondary prophylaxis)
- Patients with high-risk GV suitable for primary prophylaxis according to Baveno VI consensus.
Exclusion
- Gastro-esophageal varices type I (GOV I) will be excluded as they can be successfully treated by endoscopic band ligation.
- Pregnancy,
- Hepatorenal syndrome
- Multi-organ failure,
- platelet count less than 50,000/ml
- International Normalized Rate (INR) \>2,
- esophageal stricture,
- Splenic vein thrombosis
- Portal vein thrombosis
- Allergy to iodine.
Key Trial Info
Start Date :
July 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2018
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03277937
Start Date
July 1 2015
End Date
June 1 2018
Last Update
November 20 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ecuadorian Institute of Digestive Diseases, Omnihospital
Guayaquil, Guayas, Ecuador, 090505