Status:

COMPLETED

Development of Visual Function Evaluation Method

Lead Sponsor:

Astellas Pharma Inc

Conditions:

Retinitis Pigmentosa

Eligibility:

All Genders

20+ years

Brief Summary

The objective of this study is to develop the comprehensive visual function evaluation method in severe visually impaired patient

Detailed Description

This study is a prospective observational study which consists of 4 Parts; Part 1A, 1B, 2 and 3. Part 1A has been conducted on 6 subjects diagnosed with retinitis pigmentosa. Additional examination wi...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for patients with retinitis pigmentosa:
  • Age: ≥ 20 years
  • Subjects with severe visual disturbance (count-fingers or worse vision for severe eyes) at the time of obtaining the consent
  • Inclusion Criteria for healthy Volunteers:
  • Age: ≥ 35 and ≤ 75 years
  • Subjects with corrected visual acuity ≥ 1.0 with both eyes and without severe refractive error nor abnormal findings in slit-lamp microscopy, OCT, fundoscopy and pupillary function test at screening
  • Exclusion Criteria:
  • Subjects who have participated in any other clinical trial or clinical study involving visual function evaluation within 6 months
  • Subjects who have history of surgery, past history, and complications (cardiac/ hepatic/ renal/ respiratory/ hematological diseases, optic nerve diseases causing marked loss of visual field, and uveitis etc.) that potentially affect evaluation and safety of the study
  • Pregnant women
  • Subjects who are judged that continuation of the study is difficult during the study period
  • Subjects who are employed by the company sponsoring this study, an organization or institution related to this study

Exclusion

    Key Trial Info

    Start Date :

    November 1 2017

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    November 21 2019

    Estimated Enrollment :

    18 Patients enrolled

    Trial Details

    Trial ID

    NCT03281005

    Start Date

    November 1 2017

    End Date

    November 21 2019

    Last Update

    October 21 2024

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Site JP00001

    Meguro-ku, Tokyo, Japan