Status:
COMPLETED
tDCS Stimulation to Treat Patients With Severe and Resistant Obsessive Compulsive Disorder-Pilot Study
Lead Sponsor:
Centre Hospitalier Henri Laborit
Conditions:
Obsessive-compulsive Disorders and Symptoms
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose is to show that bifocal tDCS with an anodal stimulation on the orbitofrontal cortex and cathodic stimulation on supplementary motor areas is an effective treatment for patients with resist...
Eligibility Criteria
Inclusion
- Patients must present all of the following criteria in order to be eligible:
- Meets criteria for obsessive compulsive disorder according to DSM-IV with a "good insight" (BABS),
- Age: Participants will be both males and females, 18-70 years of age included.
- No current depressive and suicidal risks,
- No epileptic pathology,
- Chronic evolution ( Total Y-BOCS\>20 ),
- Obsessive compulsive disorder resistant to pharmacology treatment, at least 2 antidepressants (type IRS) or cognitive and comportment therapy since at least one year,
- Stability treatment (antidepressants) for more than 12 weeks without significant improvement,
- Affiliation to a social security system (recipient or assignee),
- Signed written inform consent form.
Exclusion
- Female subject who is pregnant, or of child-bearing age, sexually active and not using reliable contraception or who is nursing,
- Patient under curators
- Meets another diagnosis of axe 1 of DSM-IV,
- Current depressive or suicidal risks,
- Patient with a benzodiazepine treatment,
- Patient with any form of metal in the cranium, a pacemaker, skull defects, or skin lesions to the scalp (cuts, abrasions, rash) ,
- Epileptic patient,
- Patient with a medical history of cranial trauma,
- Patient unable to give his or hers informed consent.
Key Trial Info
Start Date :
February 19 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 12 2017
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03284671
Start Date
February 19 2016
End Date
May 12 2017
Last Update
September 15 2017
Active Locations (1)
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1
Centre Hospitalier Henri Laborit
Poitiers, France, 86021