Status:
COMPLETED
HMB for Denutrition in Patients With Cirrhosis (HEPATIC)
Lead Sponsor:
Instituto Aragones de Ciencias de la Salud
Collaborating Sponsors:
Refbio2: Trans-Pyrenean cooperation network for biomedical research
Conditions:
Sarcopenia
Cirrhosis
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
Cirrhosis is a late stage of hepatic fibrosis caused by many forms of liver diseases and conditions, such as hepatitis and chronic alcoholism. The World Health Organization (WHO) has reported that thi...
Detailed Description
1\. Scientific \& technical aspects State of the art: Patients with cirrhosis present a chronic inflammatory state and alterations in protein metabolism. These alterations lead to elevated levels of...
Eligibility Criteria
Inclusion
- negative for hepatitis C virus (HCV)\&hepatitis B virus (HBV) , or alcohol-caused cirrhosis in stable clinical condition,
- alcoholic patients must have been abstinent for at least 6 months and be in Child's score of ≤7,
- no gastrointestinal bleeding for at least 3 months,
- no clinical, microbiological, or laboratory evidence of infection, renal failure, encephalopathy, malignancy, diabetes mellitus, comorbidities including heart failure or pulmonary disease,
- No use of medications that affect protein turnover, including corticosteroids and β-blockers.
Exclusion
- \-
Key Trial Info
Start Date :
October 15 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2019
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT03285217
Start Date
October 15 2017
End Date
December 31 2019
Last Update
May 4 2021
Active Locations (1)
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1
Hospital Universitario Miguel Servet
Zaragoza, Spain, 50009