Status:
COMPLETED
Oral Cell DNA Adducts in Smokers
Lead Sponsor:
University of Minnesota
Collaborating Sponsors:
University of Hawaii
Conditions:
Lung Cancer
Eligibility:
All Genders
18+ years
Brief Summary
DNA adducts in the oral mucosa cells of 100 smokers from 3 ethnic groups - Native Hawaiians, Whites, and Japanese Americans with differing risks for lung cancer upon cigarette smoking will be quantifi...
Detailed Description
Using high resolution mass spectrometry, quantify known DNA adducts in oral mucosa cells of 100 smokers from each ethnic group - Native Hawaiians, Whites, and Japanese Americans. DNA adducts of tobacc...
Eligibility Criteria
Inclusion
- currently smoke at least 5 cigarettes per day, self-identified Japanese Americans, European Americans, or Native Hawaiians.
Exclusion
- no current use of other nicotine containing products, no acute or uncontrolled medical or psychiatric conditions, no greater than 14 alcoholic drinks per week, not pregnant, not breastfeeding, not currently taking any medications that affect relevant metabolic enzymes, no active infection.
Key Trial Info
Start Date :
February 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2021
Estimated Enrollment :
281 Patients enrolled
Trial Details
Trial ID
NCT03285893
Start Date
February 1 2018
End Date
August 1 2021
Last Update
November 12 2024
Active Locations (1)
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1
Tobacco Use Research Center
Minneapolis, Minnesota, United States, 55455