Status:

UNKNOWN

Analysis of Nutrition During Chemoradiotherapy in Patients With Gastrointestinal Cancer

Lead Sponsor:

Fudan University

Collaborating Sponsors:

The First Affiliated Hospital with Nanjing Medical University

Hubei Cancer Hospital

Conditions:

Nutritional Status

Gastrointestinal Cancer

Eligibility:

All Genders

18-70 years

Brief Summary

To assess the effectiveness of close and intense monitoring on nutritional status of gastrointestinal cancer patients during chemoradiotherapy (CRT), 500 CRT patients diagnosed with gastrointestinal s...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for Gastric Cancer:
  • pathological confirmed adenocarcinoma
  • clinical stage T3-4 and/or N+ after radical surgery
  • without distance metastases
  • KPS \>=70
  • without previous radiotherapy
  • sign the inform consent
  • Inclusion Criteria for Rectal Cancer:
  • pathological confirmed adenocarcinoma
  • clinical stage T3-4 and/or N+
  • the distance from anal verge less than 12 cm
  • without distance metastases
  • KPS \>=70
  • without previous anti-cancer therapy
  • sign the inform consent
  • Exclusion Criteria:
  • pregnancy or breast-feeding women
  • serious medical illness
  • baseline blood and biochemical indicators do not meet the following criteria: neutrophils≥1.5×10\^9/L, Hb≥90g/L, PLT≥100×10\^9/L, ALT/AST ≤2.5 ULN, Cr≤ 1 ULN
  • DPD deficiency

Exclusion

    Key Trial Info

    Start Date :

    September 1 2017

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    October 1 2021

    Estimated Enrollment :

    500 Patients enrolled

    Trial Details

    Trial ID

    NCT03286348

    Start Date

    September 1 2017

    End Date

    October 1 2021

    Last Update

    September 18 2017

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Zhen Zhang

    Shanghai, Shanghai Municipality, China, 200032