Status:
COMPLETED
Increasing the Oral Bioavailability of 6-prenylnaringenin by Micellar Solubilization
Lead Sponsor:
University of Hohenheim
Collaborating Sponsors:
Universität Tübingen
Conditions:
Safety of Native vs. Micellar 6-PN After Oral Intake
Pharmacokinetics of Native vs. Micellar 6-PN After Oral Intake
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
Micellar encapsulation will be tested to increase the oral bioavailability in humans of 6-prenylnaringenin (6-PN) from hops (Humulus lupulus). The study follows a single dose (250 mg 6-PN), placebo co...
Eligibility Criteria
Inclusion
- Healthy volunteers with blood chemistry values within normal ranges
- Age: 18-45 years
- BMI: 19-25 kg/m2
Exclusion
- Pregnancy or lactation
- Alcohol and/or drug abuse
- Use of dietary supplements or any medications, except contraceptives
- Any known malignant, metabolic and endocrine diseases
- Previous cardiac infarction
- Dementia
- Participation in a clinical trial within the past 6 weeks prior to recruitment
- Physical activity of more than 5 h/wk
Key Trial Info
Start Date :
June 22 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2018
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT03286777
Start Date
June 22 2017
End Date
July 1 2018
Last Update
October 10 2018
Active Locations (2)
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1
University of Hohenheim
Stuttgart, Baden-Wurttemberg, Germany, 70599
2
Eberhard Karls University Tuebingen
Tübingen, Baden-Wurttemberg, Germany, 72076