Status:
UNKNOWN
Novel Blood-based Colorectal Cancer Screening Method Using Natural Killer Cell Activity and Gene Panel Expression
Lead Sponsor:
Yonsei University
Conditions:
Colorectal Adenoma
Colorectal Cancer
Eligibility:
All Genders
40+ years
Brief Summary
Natural killer cells (NK cells) are cytotoxic lymphocytes that play an important role in the innate immune system. In particular, it plays a very important defense function against host cells or cance...
Eligibility Criteria
Inclusion
- Adults population over 40 years of age
- Patients who understood this study process and agreed to participation of this study
- Colon cancer patients who have been confirmed as colorectal cancer by endoscopic biopsy within 1 month
- Colon cancer patients who received no anticancer treatment such as surgery, chemotherapy, radiation therapy after cancer diagnosis.
- Colorectal adenoma and normal control group: Patients undergoing colonoscopy for diagnostic purposes or colorectal cancer screening.
Exclusion
- Patients who did not agree to participate in the study and did not write their informed consent
- Vulnerable subjects with mental retardation or severe psychiatric illness.
- Patients who are not appropriate enrollment of this study by researchers judgement.
- Patients who have had an immunosuppressive drug within 6 months.
Key Trial Info
Start Date :
June 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2019
Estimated Enrollment :
964 Patients enrolled
Trial Details
Trial ID
NCT03289988
Start Date
June 1 2017
End Date
August 1 2019
Last Update
January 15 2019
Active Locations (1)
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1
Department of Internal Medicine, Yonsei University College of Medicine
Seoul, South Korea, 120-752