Status:
COMPLETED
O2 Tension During TAVI
Lead Sponsor:
Seoul National University Hospital
Conditions:
Troponin
Eligibility:
All Genders
20-99 years
Phase:
NA
Brief Summary
Hyperoxemia can produce various complications including oxidative stress and myocardial injury. We hypothesized that the normoxic group would have lower myocardial injury compared to hyperoxic group a...
Detailed Description
Hyperoxemia can produce various complications, such as excessive oxidative stress, hyperoxia-induced vasoconstriction, increased perfusion heterogeneity, and resultant myocardial injury. Previous stud...
Eligibility Criteria
Inclusion
- Scheduled for transcatheter aortic valve replacement due to aortic stenosis
Exclusion
- Transapical approach
- Pre-procedural PaO2 \< 65 mmHg or oxygen support therapy
- Pre-procedural severe kidney injury (end-stage renal disease)
- Pre-procedural chronic pulmonary disease, symptomatic asthma
- Pre-procedural Tb-destroyed lung
- Lung cancer
- History of acute coronary syndrome within 6 months
- Pre-procedural elevated Troponin I or CKMB
- History of stroke or transient ischemic attack within 6 months
- Refuse to participate
- Pregnant
Key Trial Info
Start Date :
October 18 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 18 2022
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT03291210
Start Date
October 18 2017
End Date
July 18 2022
Last Update
July 19 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Seoul National University Hospital
Seoul, South Korea, 03080