Status:

UNKNOWN

Antimullerian Hormone as an Indicator for Ovarian Response

Lead Sponsor:

Ain Shams Maternity Hospital

Conditions:

Infertility, Female

Eligibility:

FEMALE

20-40 years

Brief Summary

Anti Mullerian hormone (AMH) is gaining place as ovarian marker, chiefly in infertility assistance. Investigators explored its correlation with oocytes retrieval after long GnRH agonist protocol for ...

Eligibility Criteria

Inclusion

  • Age:20-40 years old
  • BMI:20-40kg/m
  • Normal baseline hormonal profile (on the 2nd day of the cycle)
  • FSH: 2.5-10.2mlU/ml
  • LH:1.9-12.5mlU/ml
  • Estradiol (E2): \<50pg/ml
  • No Endometriosis by laparoscopy
  • No prior ovarian surgery; overectomy, ovariectomy or oophrectomy
  • Female subjects who have at least 1 wash-out cycle (defined as greater than or equal to 30 days since the last dose of clomiphene citrate or gonadotrophin treatment) since the last ART cycle and/or clomiphene citrate or gonadotrophin treatment prior to starting gonadotrophin releasing hormone (GnRH) agonist therapy

Exclusion

  • 1\. Age: \<20 or \>40 years old 2. BMI: \<20 or \>40kg/m 3. Female subjects with any contraindication for pregnancy. 4. Female subjects with history of tumors of the hypothalamus \& pituitary gland.
  • 5\. Female subjects with history of ovarian, uterine or mammary cancer. 6. Female subjects with history of hypersensitivity to the active substance of the medications used for ovarian stimulation.
  • 7\. Abnormal baseline hormonal profile 8. Endometriosis by laparoscopy 9. Previous ovarian surgery; overectomy, ovariectomy or oophrectomy 10. Female subjects with abnormal gynecological bleeding of unknown etiology

Key Trial Info

Start Date :

November 10 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 10 2018

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT03291860

Start Date

November 10 2017

End Date

October 10 2018

Last Update

September 25 2017

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