Status:
ACTIVE_NOT_RECRUITING
Diffusion MRI in Cervical Spondylotic Myelopathy (CSM)
Lead Sponsor:
Washington University School of Medicine
Collaborating Sponsors:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Cervical Spondylotic Myelopathy
Eligibility:
All Genders
18-75 years
Brief Summary
Patients who have been diagnosed with Cervical Spondylotic Myelopathy will be asked to undergo an MRI using diffusion basis spectrum imaging (DBSI) technology. The patients will have this MRI preopera...
Detailed Description
CSM is the most common form of spinal cord injury and is the leading cause of progressive disability in patients over the age of 65. A major shortcoming limiting the clinical management of CSM is the ...
Eligibility Criteria
Inclusion
- History of ongoing spinal cord compression,
- clinical evidence of CSM as determined by signs and symptoms including, but not limited to loss of manual dexterity, extremity weakness, sensory abnormalities, quadriparesis, loss of proprioception, and positive Babinski's or Hoffman's sign.
Exclusion
- pregnant
- having an MRI incompatible device
- having a known diagnosis of amyotrophic lateral sclerosis, multiple sclerosis, rheumatoid arthritis, concomitant thoracic and/or lumbar stenosis, spine tumor or HIV-related myelopathy and having systemic instability or being deemed unable to tolerate standard MRI sequencing.
Key Trial Info
Start Date :
January 29 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2025
Estimated Enrollment :
71 Patients enrolled
Trial Details
Trial ID
NCT03296592
Start Date
January 29 2018
End Date
December 30 2025
Last Update
November 26 2025
Active Locations (1)
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1
Washington University
St Louis, Missouri, United States, 63110