Status:
COMPLETED
Intravenous Lidocaine Randomized Comparative Effectiveness Trial
Lead Sponsor:
Montefiore Medical Center
Conditions:
Abdominal Pain
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This is a randomized, double-blind, emergency department based, comparative effectiveness study of two medication for acute abdominal pain: intravenous lidocaine and intravenous hydromorphone. Patient...
Eligibility Criteria
Inclusion
- Eligible patients are those who present to an ED for treatment of acute abdominal pain. Acute will be defined as pain for no more than seven days. At the time of enrollment, the ED treatment plan must include use of an intravenous opioid.
Exclusion
- Patients will be excluded from participation if they have cardiac conduction system impairment (QTc duration \> 0.5s, QRS duration \> 0.12s, or PR interval duration \> 0.2s), known renal (CKD \>2) or liver disease (Childs-Pugh B or greater), are hemodynamically unstable, as determined by the attending physician, are pregnant or breastfeeding, or have a known allergy to either medication. Patients will also be excluded if they have used prescription or illicit opioids within the previous week, or if they have a chronic pain disorder, defined as use of any analgesic medication on more days than not during the month preceding the acute episode of pain. Patients weighing \< 60kg or \> 120kg will be excluded.
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Key Trial Info
Start Date :
January 10 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 28 2018
Estimated Enrollment :
154 Patients enrolled
Trial Details
Trial ID
NCT03300674
Start Date
January 10 2018
End Date
August 28 2018
Last Update
August 10 2020
Active Locations (1)
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1
Montefiore Medical Center
The Bronx, New York, United States, 10467