Status:
COMPLETED
Pregabalin Effects on Hypotensive Anesthesia During Spine Surgery.
Lead Sponsor:
Mansoura University
Conditions:
Spine Surgery
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
Elective lumbar spine surgical procedures are commonly performed under controlled hypotension during general anesthesia. That is beneficial to limit the intraoperative blood loss and transfusions and ...
Detailed Description
An arterial line will be established then general anesthesia will be conducted. After adequate preoxygenation, anesthesia induction by IV fentanyl 1.5µg/kg, propofol 2 mg/kg, and atracurium 0.5 mg/kg ...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists (ASA) score I-II
- admitted to undergo lumbar discectomy or spinal fixation surgery under general anesthesia
Exclusion
- Patients on anti-hypertensive treatment, diuretics, corticosteroids, pregabalin, gabapentin, anticonvulsants, antipsychotics,
- alcohol addiction or drug abuse
- patients with history of allergy to any drug used in the study .
- pregnant or nursing women
- patients with peripheral neuropathy, endocrinal diseases, bleeding abnormality,
- cardiac, hepatic or renal impairment
Key Trial Info
Start Date :
January 8 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2019
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT03301025
Start Date
January 8 2018
End Date
April 30 2019
Last Update
September 18 2020
Active Locations (2)
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1
Delta Hospital
Al Mansurah, Dakahlia Governorate, Egypt, 35516
2
Mansoura University Hospital
Al Mansurah, Dakahlia Governorate, Egypt, 35516