Status:
WITHDRAWN
Mitochondrial Metabolism and Hepatic Complications of Obesity
Lead Sponsor:
Nantes University Hospital
Conditions:
Obesity
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The study aims to characterize mitochondrial metabolism in the liver of obesity surgery patients and to study its relationships with hepatic steatosis, inflammation, and fibrosis.
Detailed Description
The study aims to characterize mitochondrial metabolism in the liver of obesity surgery patients and to study its relationships with hepatic steatosis, inflammation, and fibrosis. The protocols involv...
Eligibility Criteria
Inclusion
- adult men and women
- affiliated to a social security
- candidate for laparoscopic obesity surgery
Exclusion
- Excessive alcohol consumption:\> 20 g / day (woman),\> 30 g / day (male)
- Chronic viral hepatitis B or C
- Genetic hemochromatosis
- Taking the following drugs for at least 3 months up to 6 months before the scheduled date of obesity surgery: systemic corticosteroids, amiodarone, methotrexate
- Wilson's disease
- autoimmune hepatitis
- alpha 1-antitrypsin deficiency
- abetalipoproteinemia
- Contraindications to liver biopsy
Key Trial Info
Start Date :
January 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2017
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03302481
Start Date
January 1 2017
End Date
January 1 2017
Last Update
August 24 2021
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