Status:
COMPLETED
Effect of Kiwifruit on Gastrointestinal Fluid Distribution and Transit in Healthy Volunteers
Lead Sponsor:
University of Nottingham
Collaborating Sponsors:
Zespri International Limited
Conditions:
Constipation
Diet Modification
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Constipation is a widespread and common problem in which a person finds it difficult and/or painful to open their bowels. The current treatment is the use of medications called laxatives. Kiwifruit is...
Detailed Description
1. Background. Chronic constipation affects approximately 17% of the population worldwide and remains an important unmet need since patients are currently often dissatisfied with treatment Current tre...
Eligibility Criteria
Inclusion
- Healthy volunteers scoring within the normal range for bowel symptoms as assessed using the GSRS, aged 18-65 years.
Exclusion
- Inability to discontinue medication likely to alter GI transit.
- Previous gastrointestinal surgery (excluding cholecystectomy and appendectomy).
- Known inflammatory bowel disease, coeliac disease.
- Known intolerance of kiwifruit.
- Inability to discontinue drugs likely to alter gut transit.
- Subjects considered by the investigator unlikely to comply with study protocol.
Key Trial Info
Start Date :
June 27 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2018
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT03303417
Start Date
June 27 2017
End Date
June 1 2018
Last Update
June 17 2019
Active Locations (1)
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1
University of Nottingham
Nottingham, Nottinghamshire, United Kingdom