Status:

COMPLETED

Retapamulin as a Decolonizing Agent for MRSA

Lead Sponsor:

NYU Langone Health

Conditions:

MRSA

Eligibility:

All Genders

9-17 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to investigate the efficacy of retapamulin to reduce carriage of MRSA via a randomized, double-blind, placebo-controlled clinical study testing retapamulin among patients ...

Eligibility Criteria

Inclusion

  • Admission to the general pediatric floor and pediatric intensive care units at NYU Langone Medical Center or visit to study team members at ODA clinic (Park Ave locations) in Williamsburg Brooklyn.
  • Ages 9 months to 17 years
  • Residing in the zip codes which reflect Orthodox Jewish neighborhoods where there is a current outbreak of this strain of MRSA.
  • Nasal and/or rectal culture positive for mupirocin-resistant methicillin-resistant Staphylococcus aureus (MRSA)

Exclusion

  • An individual who meets any of the following criteria will be excluded from participation in this study:
  • Pregnant or lactating
  • Unable to appropriately consent
  • Open sores in either of the study sites (nares or rectum)
  • Recent surgical procedure to either study site (nares or rectum)
  • Concurrent use of Rifampin or Trimethoprim/Sulfamethoxazole
  • Current active MRSA infection
  • Immunocompromised
  • Presence of endotracheal tube, tracheostomy tube or other foreign body in upper airway

Key Trial Info

Start Date :

December 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 18 2019

Estimated Enrollment :

47 Patients enrolled

Trial Details

Trial ID

NCT03304873

Start Date

December 1 2017

End Date

March 18 2019

Last Update

March 19 2020

Active Locations (1)

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New York University School of Medicine

New York, New York, United States, 10016