Status:
COMPLETED
Use of Esophageal String Test to Understand Symptoms, Inflammation, and Function in Eosinophilic Esophagitis
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
Children's Hospital of Philadelphia
Children's Hospital Colorado
Conditions:
Eosinophilic Esophagitis
Eligibility:
All Genders
7-17 years
Phase:
NA
Brief Summary
Presently, the only method available to monitor disease activity in Eosinophilic Esophagitis (EoE) is endoscopy with pathological review of biopsies. The overall goal of this study is to determine the...
Detailed Description
When children are scheduled to undergo an endoscopy, research assistants will contact the family to arrange for the Esophageal String Test (EST) to be performed within one week of the endoscopy. The s...
Eligibility Criteria
Inclusion
- Provide signed and dated informed consent form.
- Willing to comply with all study procedures and be available for the duration of the study.
- Male or female, aged 7 to 18 years old, inclusive
- Undergoing upper Endoscopy with biopsy for clinical care at CHCO or CHOP
- Current or historical diagnosis of EoE, or suspected of having EoE
Exclusion
- Known connective tissue disease, other eosinophilic disorders
- Past history of caustic injestion, esophageal surgery or other esophageal injury
- Known inflammatory bowel disease or esophageal motility disease (achalasia)
- Unwilling or unable to swallow the EST
- Oral or intravenous steroids in the preceding 60 days (not including swallowed topical fluticasone, budesonide, etc)
- Pregnancy
- Participation in a clinical study that may interfere with participation in this study
Key Trial Info
Start Date :
May 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2019
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT03305653
Start Date
May 1 2018
End Date
March 1 2019
Last Update
July 6 2021
Active Locations (1)
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1
Children's Hospital Colorado
Aurora, Colorado, United States, 80045