Status:
UNKNOWN
mtDNA as Novel Biomarker for Intra-amniotic Infection
Lead Sponsor:
Medical University of Vienna
Conditions:
Preterm Premature Rupture of Membrane
Eligibility:
FEMALE
18-45 years
Brief Summary
Finding a predictive biomarker for IAI could improve the clinical outcome for the mother and the neonate. The aim of this study is to quantify the copy number of circulating cell-free mitochondrial DN...
Detailed Description
Background: Intra-amniotic infection (IAI) or chorioamnionitis is a common condition seen in obstetrics leading to labor abnormalities such as uterine atony, postpartum bleeding and preterm labor (Sch...
Eligibility Criteria
Inclusion
- Pregnant women 2 weeks before scheduled elective caesarian section at term (control group)
- Pregnant women in week 22+0 until week 28+0 who are admitted because of pPROM (intervention group)
- aged between 18 and 45 years
- Provide signed and dated informed consent
Exclusion
- Women younger than 18 years
- No written consent
- Patients suffering from any autoimmune disease
Key Trial Info
Start Date :
April 5 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2018
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03306719
Start Date
April 5 2017
End Date
December 31 2018
Last Update
October 11 2017
Active Locations (1)
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1
Medical University of Vienna
Vienna, Austria, 1090