Status:
COMPLETED
Effect of Reducing Sedentary Behavior on Blood Pressure
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Hypertension
Prehypertension
Eligibility:
All Genders
21-65 years
Phase:
NA
Brief Summary
This is a 2-arm, 3-month randomized trial comparing a novel sedentary behavior intervention vs. control in working adults (n=271). The primary outcome is resting systolic blood pressure (SBP) at 3 mon...
Detailed Description
Hypertension (HTN) is the most common major risk factor for cardiovascular disease (CVD), affecting 1 in 3 American adults. Also, nearly another 1 in 3 adults has prehypertension (preHTN). Moderate-to...
Eligibility Criteria
Inclusion
- Age 21-65 years
- SBP 120-159 mmHg or DBP of 80-99
- Inactive (Engages in less than 150 min/wk of moderate + 2 x vigorous intensity physical activity)
- Currently perform deskwork for ≥ 20 hr/week at a desk compatible with the sit-stand attachment
- Employment within an approximate 25-mile radius of the University of Pittsburgh
- Stable employment (≥ 3 months in current job, plan to be in current job for the next 3 months)
- Supervisor approval to join the intervention
- Possession of a cellular phone able to receive text messages
Exclusion
- SBP ≥ 160 mmHg, DBP ≥ 100 mmHg
- Use of antihypertensive or glucose controlling medication
- Comorbid condition that would limit ability to reduce sedentary behavior (e.g. musculoskeletal condition, current chemotherapy)
- History of ischemic heart disease, chronic heart failure, stroke, or chronic kidney disease
- Unable to obtain consent from primary care provider or physician to participate
- Current use of sit-stand/standing desk, sedentary behavior prompting device, enrollment in a weight loss or exercise study or program, recent (\< 1 year) or planned bariatric surgery
- Currently pregnant or pregnant in that last 6 months; breastfeeding currently or in the last 3 months
- Plans to be away from your desk for an extended period (\>1 week) during the study period
Key Trial Info
Start Date :
January 3 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 22 2022
Estimated Enrollment :
271 Patients enrolled
Trial Details
Trial ID
NCT03307343
Start Date
January 3 2018
End Date
November 22 2022
Last Update
December 19 2024
Active Locations (1)
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1
University of Pittsburgh Physical Activity and Weight Management Research Center
Pittsburgh, Pennsylvania, United States, 15216