Status:

COMPLETED

Effect of Local Intraoperative Steroid on Dysphagia After ACDF

Lead Sponsor:

Rush University Medical Center

Conditions:

Dysphagia

Eligibility:

All Genders

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine if the incidence and duration of postoperative dysphagia are improved in the participants receiving a local injection of methylprednisolone with systemic dexa...

Detailed Description

Postoperative dysphagia is a known complication of anterior cervical spinal fusion (ACF) surgery with a published incidence that ranges from 1.7% to 50.3%.1-9 The pathophysiology of post-operative dys...

Eligibility Criteria

Inclusion

  • Patients undergoing a primary 1- to 3-level ACDF:
  • (a) Diagnosis: myelopathy, radiculopathy, myeloradiculopathy, stenosis, herniated nucleus pulposus, degenerative disc disease, spondylosis, osteophytic complexes, and foraminal stenosis
  • Patients able to provide informed consent

Exclusion

  • Allergies or other contraindications to medicines in the protocol including:
  • (a) Existing history gastrointestinal bleeding
  • Existing history of dysphagia
  • Current Smokers
  • Cervical spine trauma

Key Trial Info

Start Date :

August 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 20 2019

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT03311425

Start Date

August 1 2014

End Date

July 20 2019

Last Update

November 20 2020

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