Status:
COMPLETED
HEpatic Regeneration With COupled Plasma Filtration and Adsorption for Liver Extracorporeal Detoxification
Lead Sponsor:
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Conditions:
Liver Failure, Acute
Liver Failure, Acute on Chronic
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
CPFA is currently used in the treatment of severe sepsis with the intention of removing the proinflammatory mediators from the systemic circulation. Some evidence exists about the bilirubin adsorbing ...
Detailed Description
CPFA allows an improvement of blood pressure and inflammatory response during sepsis and multiorgan failure. This extracorporeal detoxification system was developed to non-specifically remove larger m...
Eligibility Criteria
Inclusion
- Acute liver failure
- Acute on chronic liver failure
- Bridge to liver transplantation
Exclusion
- acute hemorrhage
- shock
- respiratory failure
- acute coronary syndrome
- psychiatric illnesses
Key Trial Info
Start Date :
June 6 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 21 2018
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT03312036
Start Date
June 6 2013
End Date
December 21 2018
Last Update
March 17 2021
Active Locations (1)
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1
Nephrology Dialysis and Renal Transplantation Unit, S.Orsola University Hospital
Bologna, Italy