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Status:

TERMINATED

Continuous vs Aerobic Postexercise Hypotension

Lead Sponsor:

Arizona State University

Conditions:

Postexercise Hypotension

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

This study examines the effect of obesity and gender on postexercise hypotension with three different randomized exercise protocols or varying intensity. Subjects will be separated into obese and non-...

Detailed Description

Suboptimal blood pressure, defined as \>115/75 mmHg by meta-analysis, exhibits a positive relationship with cardiovascular disease, and is the leading attributable risk factor for death. Research has ...

Eligibility Criteria

Inclusion

  • Healthy, inactive (defined as less than 60 min of moderate to vigorous physical activity per week)
  • Men (age 18-45) and non-pregnant women (age 18-55)
  • Normal BMI and waist circumference (18.5- 24.5 kg/m2 and waist \<94 cm ) OR obese (BMI \> 30kg/m2 and waist \>94 cm).
  • normotensive or prehypertensive blood pressure (SBP \<140 and DBP \<90) according to JNC guidelines.

Exclusion

  • Subjects over age (men \>45, women \> 55)
  • Subjects who register more than 60 minutes/week of moderate-to-vigorous physical activity via accelerometer
  • Subjects who classify as hypertensive (SBP \>140 or DBP \>90)
  • Subjects who answer positively (i.e. yes) on The Physical Activity Readiness Questionnaire (PAR-Q).
  • Subjects with known cardiovascular, pulmonary, renal, or metabolic disease, or are having symptoms of these disease will be excluded, following current American College of Sports Medicine guidelines (ACSM).
  • Current smokers
  • Pregnant women
  • Anyone with contraindications to vigorous exercise will be excluded from the study. -Subjects on medications used for the treatment of symptomatic cardiovascular disease will be excluded.

Key Trial Info

Start Date :

October 5 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 7 2020

Estimated Enrollment :

6 Patients enrolled

Trial Details

Trial ID

NCT03313375

Start Date

October 5 2017

End Date

February 7 2020

Last Update

February 10 2020

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Arizona Biocollaborative Building- Healthy Lifestyle research labratory

Phoenix, Arizona, United States, 85004

2

Arizona Biomedical Collaborative 1

Phoenix, Arizona, United States, 85004