Status:

WITHDRAWN

HCV Post-Exposure Prophylaxis for Health Care Workers

Lead Sponsor:

Massachusetts General Hospital

Collaborating Sponsors:

Gilead Sciences

Conditions:

Hepatitis C

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This is an unblinded, observational trial of sofosbuvir-velpatasvir in adult health care workers who are exposed to hepatitis C virus from needlestick injury with hollow-bore needles.

Detailed Description

The goal of this study is to assess the safety and tolerability of the use of sofosbuvir-velpatasvir in the setting of post-exposure prophylaxis among Health Care Workers exposed to HCV from needlesti...

Eligibility Criteria

Inclusion

  • Healthcare worker with exposure through needlestick injury with hollow-bore needles to source patients who are HCV positive
  • Healthcare worker must be HCV Ab-

Exclusion

  • HCV Ab positive
  • HCV Ab negative and HCV RNA greater than 1000 IU/ml
  • Active malignancy
  • Positive urine pregnancy test

Key Trial Info

Start Date :

August 13 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 16 2020

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT03313414

Start Date

August 13 2019

End Date

January 16 2020

Last Update

January 21 2020

Active Locations (1)

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1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114