Status:
UNKNOWN
Impact of Nuclear Human Sperm Quality on Embryo Development
Lead Sponsor:
University Hospital, Clermont-Ferrand
Collaborating Sponsors:
Service Biologie de la reproduction-CECOS
Conditions:
Spermatic Parameters
Embryonic Kinetics
Eligibility:
All Genders
18-37 years
Brief Summary
To date, none study shows the impact of human spermatozoa nuclear alteration on embryonic development kinetic with morpho-kinetics tools. In this study, Investigator analyze the possible influence of ...
Detailed Description
In recent years, there has clearly been a significant decline in male fertility in industrialized countries, particularly sperm quality. Furthermore, it is known that the quality of sperm DNA affects ...
Eligibility Criteria
Inclusion
- Couple whose wife is younger than 37
- First or second ICSI attempt at Clermont-Ferrand University hospital
- Spermatozoa's concentration after Percoll gradients discontinuous technique is greater than or equal 0.5 million of spermatozoa
- Number of oocytes injected in ICSI greater than or equal to 6
Exclusion
- If ICSI performed with testicular, epididymal or frozen spermatozoa
- If one or both of the couple take antioxidant treatments
Key Trial Info
Start Date :
January 2 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03320590
Start Date
January 2 2017
End Date
January 1 2020
Last Update
November 13 2017
Active Locations (1)
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1
CHU Clermont-Ferrand
Clermont-Ferrand, France, 63003