Status:
UNKNOWN
Adipokines of Epicardial Adipose Tissue and Atherosclerosis of Coronary Arteries
Lead Sponsor:
University Hospital, Ioannina
Conditions:
Coronary Atherosclerosis
Adipokines
Eligibility:
MALE
18+ years
Brief Summary
The aim of the study is to investigate whether the expression and production of adipokines secreted by the epicardial adipose tissue correlate with the degree of coronary atherosclerosis.
Detailed Description
The aim of the study is to investigate whether the expression and production of four adipokines \[adiponectin, omenin-1, resistin and retinol binding protein-4 (RBP4)\] secreted by the epicardial adip...
Eligibility Criteria
Inclusion
- 1\) Individuals undergoing cardiac surgery
Exclusion
- Age \< 18 years
- HbA1c \> 7.0%
- Any change of antidiabetic medication the previous 3 months before the surgery
- GFR \< 60 mL/min/1.73 m2
- Liver disease
- Cancer
- Non-treated hyperthyroidism or hypothyroidism
- Autoimmune disease
- Infection
- Any change in body weight at least 5% the previous 3 months before surgery
- Significant dehydration.
- Taking any of the following drugs the previous 3 months before surgery: hormones, antiobesity drugs
Key Trial Info
Start Date :
October 23 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 22 2018
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT03322332
Start Date
October 23 2017
End Date
January 22 2018
Last Update
October 26 2017
Active Locations (1)
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1
University Hospital of Ioannina
Ioannina, Greece