Status:
UNKNOWN
Sevoflurane, Propofol and Desflurane on POD/POCD
Lead Sponsor:
Shanghai 10th People's Hospital
Collaborating Sponsors:
Massachusetts General Hospital
Conditions:
Sevoflurane
Propofol
Eligibility:
All Genders
60+ years
Brief Summary
The investigators will perform clinical studies to test the hypothesis that participants who have total hip/knee replacement under sevoflurane, propofol or desflurane anesthesia will have different ef...
Detailed Description
Postoperative delirium (POD) and postoperative cognitive disorder (POCD) are the most common complications of geriatric surgical patients, which could cause long-term social dysfunction, high mortalit...
Eligibility Criteria
Inclusion
- 60 years old or older
- Chinese Mandarin as the native language
- scheduled to undergo hip/knee surgery under general anesthesia
- American Society of Anesthesiologists (ASA) class I-Ⅲ
Exclusion
- Prior diagnoses of neurological diseases according to ICD-10
- History of severe psychiatric disorders according to DSM-IV
- Visual or auditory defects
- Participating in the investigation of another study
Key Trial Info
Start Date :
January 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2021
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT03326960
Start Date
January 1 2016
End Date
June 30 2021
Last Update
October 22 2020
Active Locations (1)
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1
Shanghai 10th People's Hospital
Shanghai, Shanghai Municipality, China, 200072