Status:
RECRUITING
Acute Heart Failure - COngestion Repeated Evaluation (AHF-CORE)
Lead Sponsor:
Central Hospital, Nancy, France
Conditions:
Acute Heart Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The AHF-CORE study is a prospective, non-randomized, multicenter regional study. The main objective of the AHF-CORE study is to identify congestion markers (clinical, biological and ultrasound) at th...
Detailed Description
Congestion (clinical, biological and ultrasound evaluation) will be quantified at inclusion within 72 hours of admission and before hospital discharge. Follow-up at 3 months of hospital discharge wil...
Eligibility Criteria
Inclusion
- Patients hospitalized for left-sided or global acute heart failure due to exacerbation of chronic heart failure within 72 hours of admission to hospital
- Patients over 18 years old
- Person affiliated to or beneficiary of a social security plan
- Person informed about study organization and having signed the informed consent
Exclusion
- Comorbidity for which life expectancy is ≤ 3 months
- Diagnosis of heart failure made less than 3 months prior to inclusion
- Exacerbation of heart failure attributed to acute ischemic stroke (acute coronary syndrome with or without ST segment elevation)
- Dialyzed patient (peritoneal dialysis or hemodialysis) and patients with glomerular filtration rate \<15 ml / min / m2 at baseline
- History of pulmonary lobectomy or pneumonectomy
- Severe pulmonary or pleural disease preventing the reliable acquisition of pulmonary ultrasound images: severe emphysema, chronic pleurisy, pulmonary fibrosis
- Suspected cardiac amylose or proven cardiac amylose
- Woman of childbearing age without effective contraception
- Persons referred in articles L.1121-5, L.1121-7, L.1121-8 and L.1122-2 of the French Public Health Code: Pregnant, parturient or breastfeeding woman ; Minor person (non-emancipated) ; Adult person under legal protection (any form of public guardianship) ; Adult person incapable of giving consent and not under legal protection.
- Persons deprived of liberty for judicial or administrative decision
- Persons subject to psychiatric care under articles L.3212-1 and L.3213-1 of the French Public Health Code
Key Trial Info
Start Date :
February 13 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT03327532
Start Date
February 13 2018
End Date
February 1 2026
Last Update
August 31 2023
Active Locations (2)
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1
CHR Metz-Thionville - Hôpital de Mercy
Metz, Lorraine, France, 57000
2
CHRU Nancy Hôpitaux de Brabois
Vandœuvre-lès-Nancy, Lorraine, France, 54500