Status:

COMPLETED

Investigating and Characterizing the Immune Response to Prostate Cancer

Lead Sponsor:

NYU Langone Health

Conditions:

Prostate Cancer

Eligibility:

MALE

18+ years

Phase:

NA

Brief Summary

This study is a clinical study to investigate and characterize the immune response profile to four different prostate cancer treatments (total cryotherapy, focal cryotherapy, Cyberknife SBRT, and radi...

Detailed Description

The immune system plays an important role in cancer, and there is evidence that different types of cancer treatment can elicit different responses from the body's immune system. This study is designed...

Eligibility Criteria

Inclusion

  • Patient is willing and able to freely sign informed consent to enroll in the study.
  • Histologically proven Prostate Carcinoma.
  • Undergoing total cryotherapy, focal cryotherapy, Cyberknife SBRT or radical prostatectomy for prostate cancer treatment.

Exclusion

  • Has previously had a radical prostatectomy for prostate cancer.
  • Has previously received cryotherapy for prostate cancer.
  • Previous treatment with chemotherapy within the past 6 months.
  • Previous treatment with radiation within the past 18 months.
  • Has evidence of metastatic disease.
  • Has a current or history within the past 6 months of alcohol and/or substance abuse which would impair participation in the study.
  • Has a major medical disorder (i.e. uncontrolled diabetes, significant hepatic, renal or hematological disorders, recent stroke or myocardial infarction), in the opinion of the urologist, is an illness or complication which is not consistent with the protocol requirements.
  • Is not willing to undergo the necessary follow-up for the trial period.
  • Has known immunologic disease, human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS)-related illness.

Key Trial Info

Start Date :

September 14 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 25 2020

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03331367

Start Date

September 14 2017

End Date

February 25 2020

Last Update

August 7 2020

Active Locations (1)

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NYU Winthrop Hospital

Mineola, New York, United States, 11501