Status:
COMPLETED
Effects of Dietary Supplement Tauroursodeoxycholic Acid on Vascular Function
Lead Sponsor:
University of Missouri-Columbia
Conditions:
Type 2 Diabetes Mellitus
Eligibility:
All Genders
20-65 years
Phase:
NA
Brief Summary
The purpose of the present study is to determine if use of dietary supplement tauroursodeoxycholic acid enhances insulin-stimulated leg blood flow and glucose disposal.
Detailed Description
The notion that cellular stress lowers insulin-induced vasodilation is largely founded on ex vivo studies and experiments in rodents. However, it remains unknown if maintenance of cellular function wi...
Eligibility Criteria
Inclusion
- Type 2 diabetes diagnosed by primary physician
- Body mass index less then 43 kg/m2
Exclusion
- Recent weight gain or loss (\>5% body weight in the last 3 months)
- Pregnancy
- Consumption of \>14 alcoholic beverages per week
- Changes in the medication use or dose within the last 3 months
- Known cardiovascular or pulmonary disease
- Taking medication for advanced retinopathy or neuropathy
- Taking prescription anticoagulants
- Nicotine use
Key Trial Info
Start Date :
October 28 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 14 2018
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT03331432
Start Date
October 28 2015
End Date
February 14 2018
Last Update
February 19 2018
Active Locations (1)
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1
University of Missouri
Columbia, Missouri, United States, 65211