Status:
COMPLETED
Can 2 Weeks of High Intensity Interval Training in Healthy 65-85 Year-olds Improve Cardiorespiratory Fitness?
Lead Sponsor:
University of Nottingham
Conditions:
Cardiorespiratory Fitness
Eligibility:
All Genders
65-85 years
Phase:
NA
Brief Summary
The incidence of conditions requiring surgical intervention increases with age, however there is a reported decline in the rates of elective surgical procedures in those over 65. This is associated wi...
Detailed Description
The percentage of people aged \>65 y in the United Kingdom increased from 15% in 1985 to 17% in 2010, an increase of 1.7 million people. One age-associated physiological change is the reduction in vas...
Eligibility Criteria
Inclusion
- Healthy Volunteer aged 65-85
Exclusion
- Current participation in a formal exercise regime
- BMI \< 18 or \> 32 kg·m2
- Active cardiovascular disease:
- uncontrolled hypertension (BP \> 160/100),
- angina,
- heart failure (class III/IV),
- Significant arrhythmia,
- right to left cardiac shunt,
- recent cardiac event
- Taking beta-adrenergic blocking agents,
- Cerebrovascular disease: previous stroke, aneurysm (large vessel or intracranial)
- epilepsy
- Respiratory disease including: pulmonary hypertension, Significant COPD, Uncontrolled asthma, Metabolic disease: -hyper and hypo parathyroidism, -untreated hyper and hypothyroidism, Cushing's disease, type 1 or 2 diabetes
- Active inflammatory bowel or renal disease
- Malignancy
- Clotting dysfunction
- Significant Musculoskeletal or neurological disorders
- Family history of early (\<55y) death from cardiovascular disease
Key Trial Info
Start Date :
January 23 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2018
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03331679
Start Date
January 23 2018
End Date
December 1 2018
Last Update
March 12 2019
Active Locations (1)
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1
Medical School
Derby, United Kingdom, DE22 3DT