Status:

COMPLETED

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Gastroscopy Sedated by Propofol

Lead Sponsor:

RenJi Hospital

Collaborating Sponsors:

Shanghai Pudong New Area People's Hospital

Shanghai Tongji Hospital, Tongji University School of Medicine

Conditions:

Hypoxia

Gastric Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Hypoxia is the most common adverse events during sedated gastroscopy. In present study, high-flow nasal cannula oxygenation will be utilized in order to reduce the hypoxia. At the same time the feasib...

Eligibility Criteria

Inclusion

  • patients undergoing gastroscope
  • age over 18 years old
  • Signed informed consent form

Exclusion

  • Coagulation disorders or a tendency of nose bleeding;
  • An episode/exacerbation of congestive heart failure (CHF) that requires a change in medication, diet or hospitalization from any cause in the last 6 months;
  • Severe aortic stenosis or mitral stenosis;
  • Cardiac surgery involving thoracotomy (e.g., coronary artery bypass graft (CABG), valve replacement surgery) in the last 6 months;
  • Acute myocardial infarction in the last 6 months;
  • Acute arrhythmia (including any tachycardia - or bradycardia) with hemodynamic instability;
  • Diagnosed chronic obstructive pulmonary disease or current other acute or chronic lung disease requiring supplemental chronic or intermittent oxygen therapy);
  • Increased intracranial pressure;
  • ASA \>III;
  • Mouth, nose, or throat infection;
  • Fever, defined as core body temperature \> 37.5oC ;
  • Pregnancy, breastfeeding or positive pregnancy test
  • Emergency procedure

Key Trial Info

Start Date :

November 10 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 30 2018

Estimated Enrollment :

2034 Patients enrolled

Trial Details

Trial ID

NCT03332433

Start Date

November 10 2017

End Date

March 30 2018

Last Update

September 5 2018

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Shanghai Tongji Hospital

Shanghai, Shanghai Municipality, China, 200065

2

Renji hospital, School of Medicine, Shanghai Jiaotong University

Shanghai, Shanghai Municipality, China, 200127

3

Shanghai Pudong New Area People's Hospital

Shanghai, Shanghai Municipality, China