Status:

COMPLETED

Does Protein and Fat Content of Meal Increase Glucose Concentrations

Lead Sponsor:

TC Erciyes University

Collaborating Sponsors:

Hacettepe University

Conditions:

Type 1 Diabetes Mellitus

Eligibility:

All Genders

16-18 years

Phase:

NA

Brief Summary

The study investigated the effects of fat protein counting (CFP) in addition to carbohydrate (CARB) counting for calculating prandial insulin dosage on blood glucose profile in patients with type 1 di...

Detailed Description

In this single center, crossover, randomized, controlled study, control meal (SM: standard meal using carbohydrate counting method) and three test meals (HPM: high protein meal using carbohydrate coun...

Eligibility Criteria

Inclusion

  • Subjects:
  • had Type1 Diabetes for at least 1 years;
  • use multiple dose (basal-bolus) insulin therapy;
  • use fast-acting insulin analogs (lispro, glulisine, and aspart) and basal insulin analogs (detemir, glargine);
  • daily inslin dose ≥0.5 IU/kg/day.

Exclusion

  • Subjects:
  • had any restrictive food intake disorders (eg celiac disease or food allergy);
  • had any diabetes complications (eg neuropathy, nephropathy or retinopathy);
  • diagnosed for \<1 year;
  • were using corticosteroid or any medication that could effect gastric emptying;
  • did exercise or had hypoglycemia or ketoacidosis within 24 hour before the test meals;
  • had overweight or obese (BMI z score: ≥ 1SD and ≥ 2SD respectively);
  • had not on follicular or peri-ovulatory phases of their menstrual cycles (for females).

Key Trial Info

Start Date :

September 10 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 20 2014

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03333525

Start Date

September 10 2013

End Date

February 20 2014

Last Update

November 7 2017

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