Status:

COMPLETED

A Study of Long-term Baricitinib (LY3009104) Therapy in Atopic Dermatitis

Lead Sponsor:

Eli Lilly and Company

Collaborating Sponsors:

Incyte Corporation

Conditions:

Atopic Dermatitis

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the long-term safety and efficacy of baricitinib in participants with atopic dermatitis. Participants were enrolled in this study from the originating studies...

Eligibility Criteria

Inclusion

  • Have participated in previous studies (JAHL, JAHM and JAIY) and met specific completion requirements for those studies, and do not meet any of the following Exclusions:

Exclusion

  • Had investigational product permanently discontinued at any time during a previous Baricitinib study.
  • Had temporary investigational product interruption continue at the final study visit of a previous Baricitinib study and, in the opinion of the investigator, this poses an unacceptable risk for the participant's participation in the study
  • OR
  • Have not participated in previous studies (JAHL, JAHM and JAIY) and satisfy the following criteria:
  • Inclusion Criteria:
  • Have been diagnosed with moderate to severe Atopic Dermatitis for at least 12 months.
  • Have had inadequate response or intolerance to existing topical (applied to the skin) medications within 6 months preceding screening.
  • Are willing to discontinue certain treatments for eczema (such as systemic and topical treatments during a washout period).
  • Agree to use emollients daily.

Key Trial Info

Start Date :

March 28 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 12 2023

Estimated Enrollment :

1645 Patients enrolled

Trial Details

Trial ID

NCT03334435

Start Date

March 28 2018

End Date

July 12 2023

Last Update

September 3 2024

Active Locations (185)

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Page 1 of 47 (185 locations)

1

CEDIC-Centro de Investigaciones Clinicas

Caba, Buenos Aires, Argentina, C1425DES

2

Centro de Investigaciones Metabólicas (CINME)

Buenos Aires, Argentina, C1027AAP

3

Buenos Aires Skin

Ciudad Autonoma Buenos Aires, Argentina, C1055AA0

4

Fundacion CIDEA

Ciudad Autonoma Buenos Aires, Argentina, C1121ABE