Status:
UNKNOWN
Repetitive Transcranial Magnetic Stimulation in Gambling Disorder
Lead Sponsor:
ITAB - Institute for Advanced Biomedical Technologies
Conditions:
Gambling Disorder
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Background: An imbalance between prefrontal cortex (PFC) and the mesolimbic reward system has been suggested to contribute to GD. GD patients showed increased functional connectivity between regions o...
Detailed Description
Gambling Disorder (GD) is a complex addictive disorder involving fronto-striatal connectivity and prefrontal top-down control modulation of reward-related brain areas. Repetitive transcranial magnetic...
Eligibility Criteria
Inclusion
- Age 18 - 65;
- Current diagnosis of Gambling Disorder, based on the Diagnostic and Statistical Manual of Mental Disorder - Fifth Edition (DSM-5);
- Drug-free.
Exclusion
- Current DSM-V diagnosis of substance use disorders other than nicotine dependence;
- Current DSM-V diagnosis of schizophrenia, bipolar disorder, or other psychotic disorder;
- Use in the past 4 weeks of any medication with known pro-convulsant action; or current regular use of any psychotropic medications (benzodiazepines, antipsychotic medications, tricyclic antidepressants, anti-epileptics, mood stabilizers);
- Any history of any clinically significant neurological disorder, including organic brain disease, epilepsy, stroke, brain lesions, multiple sclerosis, previous neurosurgery, or personal history of head trauma that resulted in loss of consciousness for \> 5 minutes and retrograde amnesia for \> 30 minutes;
- Any personal or family history (1st degree relatives) of seizures other than febrile childhood seizures;
- Any psychiatric, medical or social condition whether or not listed above, due to which, in the judgment of the PI and after any consults if indicated, participation in the study is not in the best interest of the patient;
- For female patients: Pregnancy/breastfeeding.
Key Trial Info
Start Date :
November 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2020
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03336879
Start Date
November 1 2017
End Date
December 30 2020
Last Update
November 8 2017
Active Locations (2)
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1
Department of Neuroscience, Imaging and Clinical Sciences
Chieti, Italy, 66100
2
La Promessa ONLUS
Roma, Italy, 00192