Status:
ACTIVE_NOT_RECRUITING
The Impact of a Nutritional Supplement (Impryl®) on Male Fertility
Lead Sponsor:
Radboud University Medical Center
Collaborating Sponsors:
Goodlife Fertility B.V.
Conditions:
Male Subfertility
Eligibility:
MALE
18-50 years
Phase:
NA
Brief Summary
Infertility is a worldwide problem and about 10%-15% of all couples will be affected by the inability to have children. In approximately 50% of infertile couples a male factor is involved. Male infert...
Detailed Description
Rationale: Infertility is a worldwide problem and about 10%-15% of all couples will be affected by the inability to have children. In approximately 50% of infertile couples a male factor is involved. ...
Eligibility Criteria
Inclusion
- Couples with failure to conceive for at least 12 months and starting with EM or Couples starting with 1st/ 2nd/3rd cycle of IUI (with/without ovarian stimulation) or Couples starting with 1st/ 2nd/3rd cycle of IVF/ICSI
- Furthermore:
- Male with age 18-50 years
- Female partner with age 18-43 years
- Willing and able to give informed consent
Exclusion
- Planned or performed diagnostic testicular biopsy (TESE) or percutaneous epididymal sperm aspiration (PESA)
- Use of donor-, cryopreserved- or electro-ejaculated semen
- Ovulation induction (OI) without IUI
- IVF for an absolute tubal factor
- Embryo-transfers after cryopreservation
- Embryo-transfer after pre-implantation genetic diagnosis
- Known genetic abnormalities related to infertility
- Known urological abnormality such as a varicocele or bilateral cryptorchism
- Use of other vitamin supplements
Key Trial Info
Start Date :
April 23 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2026
Estimated Enrollment :
1200 Patients enrolled
Trial Details
Trial ID
NCT03337360
Start Date
April 23 2018
End Date
April 30 2026
Last Update
April 4 2025
Active Locations (21)
Enter a location and click search to find clinical trials sorted by distance.
1
Fertiliteitscentrum Voorburg
Voorburg, Gelderland, Netherlands
2
Jeroen Bosch Ziekenhuis
's-Hertogenbosch, Netherlands, 5200ME
3
Gelre Ziekenhuizen
Apeldoorn, Netherlands, 7334DZ
4
Rijnstate
Arnhem, Netherlands, 6815AD