Status:

COMPLETED

Efficacy of Polygonatum Sibiricum on Sleep Quality Improvement

Lead Sponsor:

Ewha Womans University

Conditions:

Healthy Adults With Subjective Sleep Complaints

Eligibility:

All Genders

20-65 years

Phase:

NA

Brief Summary

This study aims to investigate the efficacy and safety of Polygonatum sibiricum for sleep quality improvement.

Eligibility Criteria

Inclusion

  • Male and female volunteers who are between the ages of 20 and 65
  • Experienced any of the following sleep problems, at least more than once a week for more than 2 months: 1) difficulty in falling asleep or staying asleep; 2) waking up at dusk and not being able to fall asleep again; 3) not feeling refreshed even after getting some sleep.

Exclusion

  • Diagnosed with insomnia assessed with a structured interview and sleep scale measurements
  • Possibility of drug-induced sleep disorders due to current intake of medication (i.e., corticosteroid, statin, etc)
  • Had taken sleeping pills (i.e., zolpidem, benzodiazepine) during the past 2 months
  • Diagnosed with any major medical or neurological disorders assessed during medical history taking, physical examination or experimental tests.
  • Diagnosed with any axis 1 psychiatric disorders (depressive disorder, bipolar disorder, alcohol dependence, schizophrenia) evaluated with a structured instrument
  • A history of traumatic brain injury with loss of consciousness, or any contraindications to MRI (i.e., claustrophobia, metallic foreign devices in body)
  • Had taken psychotropic drugs within the past 3 months before study participation
  • Allergic to polygonatum sibiricum or experienced side effects after consumption of any product containing polygonatum sibiricum
  • Participated in another clinical trial or took other medications during the period that may influence the results of this clinical trial
  • Currently taking contraceptive pills
  • Planning for pregnancy during the period of study participation, currently pregnant or breastfeeding

Key Trial Info

Start Date :

November 7 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2017

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT03337789

Start Date

November 7 2016

End Date

December 31 2017

Last Update

January 23 2018

Active Locations (1)

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1

Ewha Womans University

Seoul, South Korea, 03759