Status:
WITHDRAWN
Understanding the Mechanisms of Diastolic Dysfunction
Lead Sponsor:
University of California, Los Angeles
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Heart Failure With Preserved Ejection Fraction
Healthy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Heart failure is a clinical syndrome marked by breathlessness, even at low levels of exertion, general fatigue, and fluid retention and is estimated to affect 5.1 million people in the United States. ...
Detailed Description
The study has three aims. The first aim of the project is to refine MRI techniques using "free-breathing" versus "breath-holding" measurements. Twenty-five normal volunteers will undergo MRI to refine...
Eligibility Criteria
Inclusion
- Healthy volunteers
- 1\. Healthy adults
- Patients with Heart Failure with Preserved Ejection Fraction
- Patient scheduled for catheterization at UCLA Medical Center
- Ejection fraction \>/= 50%
- Signs and symptoms of heart failure
- Excluded other potential non-cardiac etiologies of heart failure
Exclusion
- Healthy volunteers
- Known medical condition that impacts heart health
- Contraindications to MRI (e.g., pacemaker/ICD, or claustrophobia)
- Patients with Heart Failure with Preserved Ejection Fraction
Key Trial Info
Start Date :
June 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2022
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03340233
Start Date
June 1 2018
End Date
August 1 2022
Last Update
May 1 2019
Active Locations (1)
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1
University of California Los Angeles
Los Angeles, California, United States, 90024