Status:

UNKNOWN

Open Label Immunotherapy of Endometriosis

Lead Sponsor:

Immunitor LLC

Collaborating Sponsors:

Ekomed LLC

Conditions:

Endometriosis

Eligibility:

FEMALE

18-50 years

Phase:

PHASE2

Brief Summary

Endometriosis is a chronic gynecological disease characterized by sustained painful symptoms that are responsible for a decline in the quality of life of sufferers. Endometriosis is fairly common, aff...

Detailed Description

Anatomically endometriosis is characterized by the presence of endometrial-type mucosa outside the uterine cavity. This tissue proliferates and causes chronic inflammation resulting in pain and excess...

Eligibility Criteria

Inclusion

  • age between 18 and 50 years
  • pain visual analog scale (VAS) score over 4 (visual linear scale from 0 to 10)
  • confirmation of endometriosis by laparoscopy
  • no drugs used at least for one month prior to enrollment, i.e., estro-progestinic, progestinic, gonadotropin-releasing hormone (GnRH) agonists and antagonists as well as nonsteroidal anti-inflammatory drugs (NSAIDs)

Exclusion

  • presence of other associated diseases such as malignancies
  • concomitant use of hormonal drugs
  • menopause
  • pregnancy
  • surgery for endometriosis within the last month prior to study entry
  • unable or unwilling to give written consent patients
  • adverse reaction or hypersensitivity to active substance or excipients of V-Endo

Key Trial Info

Start Date :

October 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2019

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03340324

Start Date

October 1 2017

End Date

December 1 2019

Last Update

April 16 2019

Active Locations (1)

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1

Immunitor LLC

Ulaanbaatar, Mongolia