Status:

COMPLETED

Effect of Preoperative Diclofenac Potassium on Postoperative Endodontic Pain

Lead Sponsor:

Cairo University

Conditions:

Pulpitis - Irreversible

Eligibility:

All Genders

18-60 years

Phase:

PHASE2

PHASE3

Brief Summary

The purpose of this study is to assess the effect of preoperative a single-dose of 50 mg diclofenac potassium on postoperative endodontic pain in mandibular molars with symptomatic irreversible pulpit...

Detailed Description

Patients with moderate-to-severe preoperative pain are selected. Patients receive either a single-dose of 50 mg diclofenac potassium (group A) or a placebo tablet as a control (group B). All patients ...

Eligibility Criteria

Inclusion

  • Patients with active pain (moderate-to-severe) in mandibular molars.
  • Patients with prolonged response to cold testing and electric pulp tester.
  • Patient with the ability to understand and use pain scales.
  • Patient with vital coronal pulp tissue on access.
  • Patient who accept to enroll to the study.

Exclusion

  • Patients' allergies or any other contraindication to diclofenac potassium or articaine.
  • Pregnant and lactating females.
  • Patients having pain medication in the last 6 hours.
  • Patient has more than one symptomatic mandibular tooth in the same quadrant.
  • Patients with periradicular pathosis and/or radiolucency other than widened periodontal ligaments.
  • Patients with active peptic ulcer and gastrointestinal disorders.
  • Patients with history of bleeding problems or anticoagulant use within the last month.

Key Trial Info

Start Date :

December 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2018

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT03341260

Start Date

December 1 2016

End Date

April 1 2018

Last Update

April 9 2018

Active Locations (1)

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Dentistry Faculty

Cairo, Egypt