Status:
WITHDRAWN
Study of Low Carbohydrate Enteral Nutrition in Patients With Bacterial Septic Shock
Lead Sponsor:
Yale University
Conditions:
Bacterial Sepsis
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This pilot study aims to test the tolerability of low-carbohydrate enteral nutrition in patients with bacterial septic shock.
Detailed Description
This study seeks to assess the tolerability of utilizing low-carbohydrate nutrition in patients admitted to the MICU with bacterial septic shock. Low carbohydrate feeds have been used before in the cr...
Eligibility Criteria
Inclusion
- Patients aged 18-65 admitted to the MICU with a diagnosis of severe sepsis or septic shock
- Patients with 35 \> BMI \> 18.5
- Patients with serum pro-calcitonin \> 1 ng/mL in the first 24 hours of hospitalization
Exclusion
- Patients with chronic kidney disease as defined by glomerular filtration rate \< 60 for \> 6 months
- Patients with chronic liver disease as defined by radiographic or tissue evidence of cirrhosis or persistently abnormal liver function tests for \> 6 months
- Patients with current malignancies
- Patients with autoimmune disease on current immunotherapy
- Patients on corticosteroids at doses of prednisone or prednisone-equivalents \> 5 mg for \> 6 months
- Patients with weight-reduction surgeries
- Patients with positive viral studies in the first 24 hours of admission
Key Trial Info
Start Date :
January 8 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2022
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03343041
Start Date
January 8 2018
End Date
June 1 2022
Last Update
November 26 2021
Active Locations (1)
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1
Yale New Haven Hospital
New Haven, Connecticut, United States, 06520