Status:
UNKNOWN
The Circadian Rhythm in CusHing SyndrOme in Active Phase and dUring RemiSsion (TheHOURS)
Lead Sponsor:
University of Roma La Sapienza
Collaborating Sponsors:
Federico II University
University of Palermo
Conditions:
Cushing Syndrome
Eligibility:
All Genders
18-80 years
Brief Summary
This is an observational, open, prospective multi-centre study designed to evaluate melatonin and cortisol circadian rhythm, immunological profile and anthropometric parameters in Cushing Syndrome pat...
Detailed Description
Cushing Syndrome is a severe condition caused by prolonged exposure to high levels of glucocorticoids. This is a disease with high morbidity and mortality due to metabolic, cardiovascular, coagulativ...
Eligibility Criteria
Inclusion
- Cushing Syndrome during active phase
Exclusion
- Malignancy
- Alcoholism or drug addiction
- Psychiatric disorders
- Clinical or laboratory signs of significant cardiovascular, hepatobiliary disease
- Clinically significant renal dysfunction
- Pregnancy
- Any medication with agents which could interfere with glucocorticoid kinetics and melatonin secretion
Key Trial Info
Start Date :
November 8 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2023
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03343470
Start Date
November 8 2017
End Date
December 30 2023
Last Update
November 23 2022
Active Locations (1)
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1
Department of Experimental Medicine
Rome, Italy, 00161