Status:
TERMINATED
Accelerated rTMS for the Reduction of Nicotine Craving
Lead Sponsor:
Medical University of South Carolina
Conditions:
Nicotine Use Disorder
Nicotine Dependence
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose if this study is to determine if five treatments of repetitive transcranial magnetic stimulation (rTMS) can reduce craving for cigarettes in smokers. rTMS uses magnetic pulses to stimulate...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Outpatient Adults aged 18-70
- Cigarette Smokers smoking at least 1 pack (20 cigarettes a day) with current smoking status confirmed by exhaled CO reading of \>10ppm day of visit.
- Ability to provide informed consent
- Exclusion Criteria
- Current treatment with varenicline or bupropion
- Currently making a smoking quit attempt (not currently smoking).
- Current treatment with an antidepressant, anti-convulsant, anxiolytic, antipsychotic or mood stabilizer.
- Current episode of major depression determined by MINI interview.
- Current or past history of schizophrenia, schizoaffective disorder, anorexia nervosa, bulimia or bipolar disorder as determined by MINI.
- Current daily consumption of alcohol or current alcohol use disorder.
- Current substance use disorder except for nicotine or cannabis use disorder.
- Currently pregnant or lactating.
- Contraindications to rTMS including history of seizure, metal implanted above the neck, pacemaker or any brain lesion.
- Unstable medical conditions
- Suicidal ideation or history of suicide attempt within the last six months.
- Inability or unwillingness of subject or legal guardian/representative to give informed consent
Exclusion
Key Trial Info
Start Date :
January 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 12 2018
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT03352609
Start Date
January 1 2018
End Date
December 12 2018
Last Update
October 15 2019
Active Locations (1)
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1
MUSC Institute of Psychiatry
Charleston, South Carolina, United States, 29425