Status:
COMPLETED
The Effect of a Liraglutide on IVF in Obese PCOS
Lead Sponsor:
University Medical Centre Ljubljana
Conditions:
Polycystic Ovary Syndrome
Obesity
Eligibility:
FEMALE
18-37 years
Phase:
PHASE4
Brief Summary
The aim of this study was to evaluate the impact of low dose liraglutide in combination with metformin compared to metformin alone on IVF pregnancy rate (PR) and cumulatively PR (IVF and spontaneous) ...
Detailed Description
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility, in particular when PCOS is linked to obesity. Obese PCOS has poor IVF outcomes associated with impaired oocyte and...
Eligibility Criteria
Inclusion
- 18 years old to 38 years old
- polycystic ovary syndrome (rotterdam criteria)
- BMI of 30 kg/m² or higher
- Infertility
- Before IVF
Exclusion
- type 1 or type 2 diabetes mellitus
- history of carcinoma
- Cushing's syndrome or congenital (non-classic) adrenal hyperplasia
- personal or family history of MEN 2
- significant cardiovascular, kidney or hepatic disease
- the use of medications known or suspected to affect reproductive or metabolic functions
- the use of statins, within 90 days prior to study entry no other ovarian pathology normal male semen
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2016
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03353948
Start Date
September 1 2014
End Date
September 1 2016
Last Update
November 27 2017
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.